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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP40 All Species: 12.12
Human Site: S1226 Identified Species: 44.44
UniProt: Q9NVE5 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NVE5 NP_060688.1 1235 140130 S1226 R P R A P E T S L S I H V G S
Chimpanzee Pan troglodytes XP_516162 1234 140107 S1225 R P R A P E T S L S I H V G S
Rhesus Macaque Macaca mulatta XP_001110228 1254 141887 S1245 R T R A P E T S L S I H V G S
Dog Lupus familis XP_543294 1250 141419 A1240 G R P R A P E A S L S I H V R
Cat Felis silvestris
Mouse Mus musculus Q8BWR4 1235 139934 S1226 R F R G P E A S L S I H V A S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510790 1268 144200 A1258 V R P H K P E A A L S I N V G
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782883 1301 145969 E1280 A V S L G G G E S K E K S K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 94.8 82.2 N.A. 79.8 N.A. N.A. 66.8 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 37.3
Protein Similarity: 100 99.3 96.4 89.3 N.A. 87.6 N.A. N.A. 78.7 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 56.2
P-Site Identity: 100 100 93.3 0 N.A. 73.3 N.A. N.A. 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 93.3 6.6 N.A. 73.3 N.A. N.A. 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 0 0 43 15 0 15 29 15 0 0 0 0 15 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 58 29 15 0 0 15 0 0 0 0 % E
% Phe: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 15 0 0 15 15 15 15 0 0 0 0 0 0 43 15 % G
% His: 0 0 0 15 0 0 0 0 0 0 0 58 15 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 58 29 0 0 0 % I
% Lys: 0 0 0 0 15 0 0 0 0 15 0 15 0 15 15 % K
% Leu: 0 0 0 15 0 0 0 0 58 29 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % N
% Pro: 0 29 29 0 58 29 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 58 29 58 15 0 0 0 0 0 0 0 0 0 0 15 % R
% Ser: 0 0 15 0 0 0 0 58 29 58 29 0 15 0 58 % S
% Thr: 0 15 0 0 0 0 43 0 0 0 0 0 0 0 0 % T
% Val: 15 15 0 0 0 0 0 0 0 0 0 0 58 29 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _